The EGTC is managed by the Secretary-General. He is assisted in the General Secretariat - which runs the day to day affairs of the EGTC - by the representatives of the other two regions and takes all his decisions after their consultation. The office of the Secretary-General rotates every two years between member regions, at the same time as the Presidency. The Secretary-General is always the official of the member region holding the Presidency.
The current Secretary-General is dott.ssa Marilena Defrancesco, representative of the Autonomous Province of Trento in the EGTC’s General Secretariat.